THE ULTIMATE GUIDE TO AHU'S

Roughly eighty% of TTP is induced by deficient exercise of ADAMTS13. ADAMTS13 deficiency may be constitutive, as a result of biallelic ADAMTS13 pathogenic variants; or obtained, due to an inhibitory antibody. Analysis of ADAMTS13 action is carried out applying checks dependant on the potential of the protease to cleave conventional VWF multimers in